XRCC3 Depletion Induces Spontaneous DNA Breaks and p53-Dependent Cell Death
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چکیده
منابع مشابه
Depletion of CTCF in Breast Cancer Cells Selectively Induces Cancer Cell Death via p53
CCCTC-binding factor (CTCF), a ubiquitous 11-zinc finger multifunctional protein, has distinct molecular functions, such as transcriptional activation, repression, and chromatin barrier activity, in a locus-specific manner. Elevated CTCF levels in breast cancer cells are known to contribute to tumorigenesis; however, the underlying mechanism remains elusive. We investigated the effect of CTCF e...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2007
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.6.5.3923